As we all know stroke in human is one of the major problems as it causes sudden death of brain cells. It occurs mainly due to lack of oxygen, when the blood flow to the brain is stopped. There are two main types of strokes; one is ischemic stroke, where blockage of blood flows to a portion of brain occurs by blood clot. The other type is Hemorrhagic stroke, it is caused by the rupture of blood vessel in the brain.
During stroke, the production of thrombin (a "trypsin-like" serine protease protein that has many roles such as blood coagulation, fibrin formation, and platelet activation) is more and plays a negative role as it damages the brain cells. Previously thrombin was found only in Hemorrhagic stroke and now Patrick D. Lyden and his group have found that presence of thrombin Ischemic stroke also.
http://www.medicalnewstoday.com/releases/238238.php
http://www.cdc.gov/stroke/types_of_stroke.htm
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